VEGFR-2-IN-11
Product Specifications
UNSPSC Description
VEGFR-2-IN-11 (Compound 8h) is a potent VEGFR-2 inhibitor with an IC50 of 60.27 nM. VEGFR-2-IN-11 shows antitumor activity and induces cell apoptosis[1].
Target Antigen
Apoptosis; VEGFR
Type
Reference compound
Related Pathways
Apoptosis;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-2-in-11.html
Solubility
10 mM in DMSO
Smiles
S=C(NC1=CC=C(C=C1)NC2=NC(/C=C/C3=CC=C(C=C3)Br)=NC4=CC=CC=C42)NC5=CC=CC=C5
Molecular Weight
552.49
References & Citations
[1]Abdelrahman Hamdi, et al. Design, synthesis, antitumor, and VEGFR-2 inhibition activities of novel 4-anilino-2-vinyl-quinazolines: Molecular modeling studies. Bioorg Chem. 2022 May;122:105710.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145856/VEGFR-2-IN-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145856/
Clinical Information
No Development Reported
Curated Selection
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