GA-O-02
GA-O-02, a 18β-Glycyrrhetinic acid derivative, is a potent antimicrobial and anti-inflammatory agent. GA-O-02 exerts anti-inflammation through the inhibition of NO, pro-inflammatory cytokines and chemokines. GA-O-02 displays a high antimicrobial activity against Gram-positive bacteria[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ga-o-02.html
Solubility
10 mM in DMSO
Smiles
C[C@@]1(C(O)=O)C[C@]2([H])[C@@](C)(CC[C@@]3(C2=CC([C@@]4([C@]5(C/C(C(C(C)([C@@]5(CC[C@@]34C)[H])C)=O)=C\C6=C(C=C(C=C6)Cl)[N+]([O-])=O)C)[H])=O)C)CC1
Molecular Formula
C37H46ClNO6
Molecular Weight
636.22
References & Citations
[1]Borong Tu, et al. Novel 18β-glycyrrhetinic acid derivatives as a Two-in-One agent with potent antimicrobial and anti-inflammatory activity. Bioorg Chem. 2022 May;122:105714.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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