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C-Myc inhibitor 5

C-Myc inhibitor 5 (DA3) is a fluorescent, long chain-bridged bispurine that selectively targets the c-MYC G-quadruplex (KD of 16 μM) . c-Myc inhibitor 5 shows inhibition on c-MYC expression rather than other G4-driven oncogenes[1].

Product Specifications

UNSPSC

12352005

Target

C-Myc

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/c-myc-inhibitor-5.html

Solubility

10 mM in DMSO

Smiles

CC1CCN(CC1)C2=NC(N)=C3N=CN(C3=N2)CCCCCCCCN4C5=NC(N6CCC(C)CC6)=NC(N)=C5N=C4

Molecular Formula

C30H46N12

Molecular Weight

574.77

References & Citations

[1]Hu MH, et al. Discovery of a fluorescent, long chain-bridged bispurine that selectively targets the c-MYC G-quadruplex. Bioorg Chem. 2022;122:105750.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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