Mcl-1 inhibitor 8

Mcl-1 inhibitor 8 is a MCL-1 inhibitor, example 228, extracted from patent WO2019222112[1].

Bcl-2 Family

Reference compound

Apoptosis

Cancer-programmed cell death

Cancer

https://www.medchemexpress.com/mcl-1-inhibitor-8.html

10 mM in DMSO

ClC1=CC=C([C@@]2(CCC3)CN4C5=CC(C(N=S(NC(C6=CN(C)N=C6OC)=O)(C[C@H](C/C=C\[C@@H]([C@@]7([H])[C@](CC7)([H])C4)OC)C)=O)=O)=CC=C5OC2)C3=C1

736.32

[1]Hang CHU, et al. Inhibiteurs de mcl-1. Patent WO2019222112.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-145826/Mcl-1-inhibitor-8-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-145826/

No Development Reported

2388471-31-4