(E) -Mcl-1 inhibitor 7
(E) -Mcl-1 inhibitor 7 (Example 34) is a Mcl-1 inhibitor (Ki: IC50: [1].
Product Specifications
CAS Number
2417463-86-4
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-mcl-1-inhibitor-7.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C([C@@]2(CCC3)CN4C5=CC(S(=O)(NC(C(C)(OC/C=C\[C@@H]([C@@]6([H])[C@](CC6)([H])C4)OC(N(C)C)=O)C)=O)=O)=CC=C5OC2)C3=C1
Molecular Formula
C34H42ClN3O7S
Molecular Weight
672.23
References & Citations
[1]Zhuo, Jincong, et al. Preparation of spiro-sulfonamide derivatives as inhibitors of myeloid cell leukemia-1 (MCL-1) protein for the treatment of cancer. Patent. WO2020097577.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Mcl-1
Frequently Asked Questions
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