Tubulin inhibitor 15

Tubulin inhibitor 15 is a potent tubulin inhibitor. Tubulin inhibitor 15 shows antiproliferative activity. Tubulin inhibitor 15 shows cytotoxicity in HepG2 cells[1].

Product Specifications

CAS Number

[2767446-36-4]

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-inhibitor-15.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=CC(F)=CC=C2C=C(N1)C3=CC=CC(OC)=C3

Molecular Formula

C16H12FNO2

Molecular Weight

269.27

References & Citations

[1]Elhemely MA, et al. SAR of Novel 3-Arylisoquinolinones: meta-Substitution on the Aryl Ring Dramatically Enhances Antiproliferative Activity through Binding to Microtubules. J Med Chem. 2022 Mar 24;65 (6) :4783-4797.