Tubulin inhibitor 15
Tubulin inhibitor 15 is a potent tubulin inhibitor. Tubulin inhibitor 15 shows antiproliferative activity. Tubulin inhibitor 15 shows cytotoxicity in HepG2 cells[1].
Product Specifications
CAS Number
2767446-36-4
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-inhibitor-15.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC(F)=CC=C2C=C(N1)C3=CC=CC(OC)=C3
Molecular Formula
C16H12FNO2
Molecular Weight
269.27
References & Citations
[1]Elhemely MA, et al. SAR of Novel 3-Arylisoquinolinones: meta-Substitution on the Aryl Ring Dramatically Enhances Antiproliferative Activity through Binding to Microtubules. J Med Chem. 2022 Mar 24;65 (6) :4783-4797.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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