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Dideoxycytidinene

Dideoxycytidinene (2′,3′-Didehydro-2′,3′-dideoxycytidine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

7481-88-1

Product Name Alternative

2′,3′-Didehydro-2′,3′-dideoxycytidine

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dideoxycytidinene.html

Purity

98.36

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1C=C[C@H](N2C(N=C(N)C=C2)=O)O1

Molecular Formula

C9H11N3O3

Molecular Weight

209.20

Precautions

H315, H319, H320

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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