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Abiraterone decanoate

Abiraterone decanoate is a potent Abiraterone proagent. Abiraterone decanoate provide a controlled release of Abiraterone and long-acting CYP17 inhibition with intramuscular (IM) delivery[1].

Product Specifications

CAS Number

[2486052-18-8]

UNSPSC

12352005

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/abiraterone-decanoate.html

Purity

99.69

Solubility

DMSO : 1.92 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@@]12[C@](CC=C2C3=CN=CC=C3)([H])[C@@]4([H])[C@@](CC1)([H])[C@@]5(C(C[C@H](CC5)OC(CCCCCCCCC)=O)=CC4)C

Molecular Formula

C34H49NO2

Molecular Weight

503.76

References & Citations

[1]William R. Moore, et al. Abiraterone decanoate (AD) : Potent and long-acting activity of a novel intramuscular (IM) abiraterone prodrug depot in a castrate monkey model. Journal of Clinical Oncology, Volume 39, Issue 6_suppl.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CYP17

Available Sizes

Curated Selection

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