HIgG-hFc receptor-IN-1
HIgG–hFc receptor-IN-1 (comp 66) is a human immunoglobulin G–human neonatal Fc receptor (hIgG–hFcRn) protein-protein interaction inhibitor, with an IC50 of 2 μM [1].
Product Specifications
CAS Number
1425051-22-4
UNSPSC
12352005
Target
Fc Receptor (FcR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/higg-hfc-receptor-in-1.html
Solubility
10 mM in DMSO
Smiles
N#CC(C1=NC2=C(N=C1N3CCCCCC3)C=CC=C2)C(NC(CN4CCOCC4)C5=CC=C(C=C5)OC)=O
Molecular Formula
C30H36N6O3
Molecular Weight
528.65
References & Citations
[1]Zhaolin Wang, et al. Discovery and structure-activity relationships of small molecules that block the human immunoglobulin G-human neonatal Fc receptor (hIgG-hFcRn) protein-protein interaction. Bioorg Med Chem Lett. 2013 Mar 1;23 (5) :1253-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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