PD-1/PD-L1-IN-22
PD-1/PD-L1-IN-22 (Example 2) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-22 blocks PD-1/PD-L1 with the IC50 of 0.732 μM. PD-1/PD-L1-IN-22 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].
Product Specifications
CAS Number
2159063-12-2
UNSPSC
12352005
Target
PD-1/PD-L1
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pd-1-pd-l1-in-22.html
Solubility
10 mM in DMSO
Smiles
O=C(C)NCCNCC1=CC(Cl)=C(C=C1OC)OCC2=CC=CC(C3=CC=CC=C3)=C2Br
Molecular Formula
C25H26BrClN2O3
Molecular Weight
517.84
References & Citations
[1]Phenylate derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202276A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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