PD-1/PD-L1-IN-20
PD-1/PD-L1-IN-20 (Example 21) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-20 blocks PD-1/PD-L1 with the IC50 of 5.29 nM. PD-1/PD-L1-IN-20 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].
Product Specifications
CAS Number
2159138-01-7
UNSPSC
12352005
Target
PD-1/PD-L1
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pd-1-pd-l1-in-20.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=CC(COC2=CC(OCC3=CC=CC(C4=CC=CC=C4)=C3Br)=C(C=C2CNCCO)Cl)=C1
Molecular Formula
C30H26BrClN2O3
Molecular Weight
577.90
References & Citations
[1]Benzyl phenyl ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202273A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Human Sodium-dependent phosphate transport protein 2B (SLC34A2) -VLPs
Recombinant Human Sodium-dependent phosphate transport protein 2B (SLC34A2) -VLPs
Recombinant Human Sodium-dependent phosphate transport protein 2B (SLC34A2) -VLPs