Dual AChE-MAO B-IN-2
Product Specifications
UNSPSC Description
Dual AChE-MAO B-IN-2 is a potent AChE and MAO B dual inhibitor with IC50s of 0.12 μM and 0.01 μM for b>AChE and MAO B, respectively. Dual AChE-MAO B-IN-2 has the potential for the research of Alzheimer’s disease[1].
Target Antigen
Cholinesterase (ChE); Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dual-ache-mao-b-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2=C(C(CO)=C1)C=CC(OCC3=CC=C(CN(CC4=CC=CC=C4)C)C=C3)=C2
Molecular Weight
415.48
References & Citations
[1]Ekström F, et al. Dual Reversible Coumarin Inhibitors Mutually Bound to Monoamine Oxidase B and Acetylcholinesterase Crystal Structures. ACS Med Chem Lett. 2022, 13(3):499-506.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145708/Dual-AChE-MAO-B-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145708/
Clinical Information
No Development Reported
CAS Number
1801157-64-1
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