UCSF648
UCSF648 (Compound 5A6-48) is a chemical probe for the 5-HT5A serotonin receptor. UCSF648 weakly activates ADRA2A and MTNR1A[1].
Product Specifications
CAS Number
[2637090-55-0]
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ucsf648.html
Solubility
10 mM in DMSO
Smiles
O=S(CC)(CCCNCC1=CC=C(C2=CC=CN=C21)Cl)=O
Molecular Formula
C15H19ClN2O2S
Molecular Weight
326.84
References & Citations
[1]Levit Kaplan A, et al. Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor. J Med Chem. 2022 Mar 10;65 (5) :4201-4217.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT5 Receptor; Prostaglandin D Synthase
Curated Selection
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