UCSF648

UCSF648 (Compound 5A6-48) is a chemical probe for the 5-HT5A serotonin receptor. UCSF648 weakly activates ADRA2A and MTNR1A[1].

Product Specifications

CAS Number

[2637090-55-0]

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ucsf648.html

Solubility

10 mM in DMSO

Smiles

O=S(CC)(CCCNCC1=CC=C(C2=CC=CN=C21)Cl)=O

Molecular Formula

C15H19ClN2O2S

Molecular Weight

326.84

References & Citations

[1]Levit Kaplan A, et al. Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor. J Med Chem. 2022 Mar 10;65 (5) :4201-4217.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT5 Receptor; Prostaglandin D Synthase

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