DCCCyB
DCCCyB is an orally bioavailable, potent, and selective inhibitor of GlyT1. DCCCyB demonstrates excellent in vivo occupancy of GlyT1 transporters in rhesus monkey[1].
Product Specifications
CAS Number
[1236046-15-3]
UNSPSC
12352005
Target
GlyT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dcccyb.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C=C(C=C1)Cl)Cl)NC[C@@]2(CC[C@@H](CC2)S(CC3CC3)(=O)=O)CC4CC4
Molecular Formula
C22H29Cl2NO3S
Molecular Weight
458.44
References & Citations
[1]Blackaby WP, et al. Identification of an Orally Bioavailable, Potent, and Selective Inhibitor of GlyT1. ACS Med Chem Lett. 2010;1 (7) :350-354.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14568/DCCCyB-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14568/
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
GlyT1
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