CDK7-IN-11
CDK7-IN-11 is an orally active CDK7 inhibitor. CDK7-IN-11 exhibits high CDK7 inhibitory activity with IC50 value of 4.2 nM. CDK7-IN-11 can be effectively used for the research of diseases associated with CDK7[1].
Product Specifications
CAS Number
2414896-32-3
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk7-in-11.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC(C2=CC([C@H](C)C(NC3=NC=C(CC)S3)=O)=CC=C2)=CN=C1NC(/C=C/CN(C)C)=O
Molecular Formula
C26H28N6O2S
Molecular Weight
488.60
References & Citations
[1]Novel cdk7 inhibitory compound or pharmaceutically acceptable salt thereof. Patent. WO2021182914A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK7
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