Aminooxy-PEG2-BCN

Aminooxy-PEG2-BCN is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Aminooxy-PEG2-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Product Specifications

CAS Number

[2253965-14-7]

UNSPSC

12352203

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aminooxy-peg2-bcn.html

Purity

Solubility

10 mM in DMSO

Smiles

O=C(NCCOCCOCCNC(CON)=O)OCC1C2CCC#CCCC12

Molecular Formula

C19H31N3O6

Molecular Weight

397.47

References & Citations

[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16 (5) :315-337.

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker

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