Onfasprodil
Onfasprodil is negative allosteric modulator of NR2B. Onfasprodil in combination with GABA receptor regulator has the potential for the research of Alzheimer's disease (extracted from patent CN111481543A) [1].
Product Specifications
CAS Number
1892581-29-1
Product Name Alternative
MIJ-821
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/onfasprodil.html
Solubility
10 mM in DMSO
Smiles
O[C@H](C1=CC=C(C=N1)O)CN(C2)C[C@](C3)([H])[C@@]2([H])C[C@H]3OC4=C(C=CC=C4)F
Molecular Formula
C20H23FN2O3
Molecular Weight
358.41
References & Citations
[1]Liu, Shanglian, et al. Use of NR2B negative allosteric modulators in combination with GABA receptor modulators for the preparation of a medicament for the treatment of Alzheimer's disease. Patent CN111481543A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
