Itruvone

Itruvone is a intermediate of 17α-ethinylestradiol (EE2) during Fenton oxidation. Itruvone has an antidepressant effect[1][2]. Itruvone is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[21321-89-1]

Product Name Alternative

PH10

UNSPSC

12352211

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/itruvone.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@]3([H])[C@](CCC1=CC(CC2)=O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)C#C)C

Molecular Formula

C21H28O

Molecular Weight

296.45

References & Citations

[1]Louis Monti. Use of pregn-4-en-20-yn-3-one for the treatment of depressive disorders. Patent WO2014105620 A1.|[2]Li Y, et al. Removal of steroid estrogens from waste activated sludge using Fenton oxidation: influencing factors and degradation intermediates. Chemosphere. 2014 Jun;105:24-30.