CL2-MMT-SN38
CL2-MMT-SN38 is a SN-38 derivative. SN-38, an anticancer agent, is an active metabolite of the Topoisomerase I inhibitor Irinotecan (CPT-11) [1].
Product Specifications
CAS Number
1084888-82-3
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cl2-mmt-sn38.html
Solubility
10 mM in DMSO
Smiles
O=C(C1CCC(CC1)CN2C(C=CC2=O)=O)NCC(N=N3)=CN3CCOCCOCCOCCOCCOCCOCCOCCOCCNC(COCC(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(NC5=CC=C(C=C5)COC(O[C@]6(C7=C(COC6=O)C(N8C(C(C(C8)=C(C9=C%10)CC)=NC9=CC=C%10O)=C7)=O)CC)=O)=O)CCCCNC(C%11=CC=CC=C%11)(C%12=CC=CC=C%12)C%13=CC=C(C=C%13)OC)=O)=O)=O
Molecular Formula
C102H122N12O24
Molecular Weight
1900.13
References & Citations
[1]Moon SJ, et al. Antibody conjugates of 7-ethyl-10-hydroxycamptothecin (SN-38) for targeted cancer chemotherapy. J Med Chem. 2008;51 (21) :6916-6926.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC682050-500 1x 500 µL
Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details ![PerCP/Cyanine5.5 Anti-Mouse CD48 Antibody[HM48-1]](https://cdn.genprice.uk/products/763/68dd1494061270361e7cd4fd/imageurl/e-ab-f1017uj.webp)
E-AB-F1017UJ-01 25 µg
PerCP/Cyanine5.5 Anti-Mouse CD48 Antibody[HM48-1]
Sign In for Pricing
View Details E-AB-F1017UJ-02 100 µg
PerCP/Cyanine5.5 Anti-Mouse CD48 Antibody[HM48-1]
Sign In for Pricing
View Details 