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PROTAC IRAK4 ligand-3

Product Specifications

UNSPSC Description

PROTAC IRAK4 ligand-3 is a ligand of PROTAC KT-474 (HY-145483) that can be used in cancer research[1].

Target Antigen

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-irak4-ligand-3.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(N=C(N2[C@@H](CO3)C[C@@H]3C2)C=C4)N4N=C1)NC5=CN(N=C5C(F)F)[C@@]6([H])CC[C@@H](CC6)C=O

Molecular Weight

485.49

References & Citations

[1]ZHENG XZ, et al. Fused heterocyclic compounds as IRAK4 degraders and their preparation, pharmaceutical compositions and use in the treatment of diseases. WO2022125790. 2022.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-145484/PROTAC-IRAK4-ligand-3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-145484/

Clinical Information

No Development Reported

CAS Number

2434848-46-9

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