PROTAC IRAK4 ligand-3
PROTAC IRAK4 ligand-3 is a ligand of PROTAC KT-474 (HY-145483) that can be used in cancer research[1].
Product Specifications
CAS Number
[2434848-46-9]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-irak4-ligand-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(N=C(N2[C@@H](CO3)C[C@@H]3C2)C=C4)N4N=C1)NC5=CN(N=C5C(F)F)[C@@]6([H])CC[C@@H](CC6)C=O
Molecular Formula
C23H25F2N7O3
Molecular Weight
485.49
References & Citations
[1]ZHENG XZ, et al. Fused heterocyclic compounds as IRAK4 degraders and their preparation, pharmaceutical compositions and use in the treatment of diseases. WO2022125790. 2022.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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