Colistin adjuvant-1
Colistin adjuvant-1 is a colistin adjuvant, shows increased colistin potentiation activity against Gram-negative bacteria. Colistin adjuvant-1 inhibits NF-κB with an IC50 of 0.209 μM[1].
Product Specifications
CAS Number
[2862800-15-3]
UNSPSC
12352005
Target
Bacterial; NF-κB
Type
Reference compound
Related Pathways
Anti-infection; NF-κB
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/colistin-adjuvant-1.html
Solubility
10 mM in DMSO
Smiles
OC(C=C(C(F)(F)F)C=C1)=C1C2=NC3=C(C(F)(F)F)C=C(C(F)(F)F)C=C3N2
Molecular Formula
C16H7F9N2O
Molecular Weight
414.23
References & Citations
[1]Li H, et al. Benzimidazole Isosteres of Salicylanilides Are Highly Active Colistin Adjuvants. ACS Infect Dis. 2021 Nov 9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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