Colistin adjuvant-1
Colistin adjuvant-1 is a colistin adjuvant, shows increased colistin potentiation activity against Gram-negative bacteria. Colistin adjuvant-1 inhibits NF-κB with an IC50 of 0.209 μM[1].
Product Specifications
CAS Number
[2862800-15-3]
UNSPSC
12352005
Target
Bacterial; NF-κB
Type
Reference compound
Related Pathways
Anti-infection; NF-κB
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/colistin-adjuvant-1.html
Solubility
10 mM in DMSO
Smiles
OC(C=C(C(F)(F)F)C=C1)=C1C2=NC3=C(C(F)(F)F)C=C(C(F)(F)F)C=C3N2
Molecular Formula
C16H7F9N2O
Molecular Weight
414.23
References & Citations
[1]Li H, et al. Benzimidazole Isosteres of Salicylanilides Are Highly Active Colistin Adjuvants. ACS Infect Dis. 2021 Nov 9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
035281-APC 200 µL
EXTL3, NT (EXTL3, EXTL1L, EXTR1, KIAA0519, Exostosin-like 3, EXT-related protein 1, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, Multiple exostosis-like protein 3, Putative tumor suppressor protein EXTL3) (APC) discontinued
Ask
View Details 
