IL-17 modulator 5
IL-17 modulator 5 (compound 26) is a IL-17 inhibitor, with an IC50 of 1 nM[1].
Product Specifications
CAS Number
2724206-27-1
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/il-17-modulator-5.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NON=C1C)N[C@H](C2=NC3=CC=C([C@@H](C4=NN=C5C=CC(C#N)=CN54)CC(F)(F)F)C(F)=C3N2)C6CCC(F)(F)CC6
Molecular Formula
C28H23F6N9O2
Molecular Weight
631.53
References & Citations
[1]Ram W Sabnis, et al. Novel Difluorocyclohexyl Derivatives as IL-17 Modulators for Treating Inflammatory and Autoimmune Diseases. ACS Med Chem Lett. 2021 Nov 18;12 (12) :1883-1884.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-17
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