DYSP-C34
DYSP-C34 is a potent, biocompatible, and ultrasound (US) -triggered multifunctional molecular machine. DYSP-C34 has multiple favorable properties, such as improved lipophilic/hydrophilic balance, intensified US-induced ROS production capacity, and better cellular permeability, resulting in the excellent tumor target efficiency and notable sonodynamic therapy (SDT) -mediated tumor regression. DYSP-C34 exhibits mild immunogenicity by stimulating APCs directly[1].
Product Specifications
CAS Number
[2559734-98-2]
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dysp-c34.html
Solubility
10 mM in DMSO
Smiles
OC(C[C@@H](C(O)=O)NC(C/C1=C(C(C(O)=O)=C/2C)/NC2=C/C(C(CC)=C/3C)=NC3=C/C(N4)=C(/C=C/C5=CC=C(C=C5)OC)C(C)=C4/C=C6[C@@H](C)[C@H](CCC(O)=O)C1=N/6)=O)=O
Molecular Formula
C45H47N5O10
Molecular Weight
817.88
References & Citations
[1]Wang L, et al. An ultrasound-driven immune-boosting molecular machine for systemic tumor suppression. Sci Adv. 2021;7 (43) :eabj4796.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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