Miaosporone A
Product Specifications
UNSPSC Description
Miaosporone A, an angucyclic quinone, exhibits antimalarial activity against Plasmodium falciparum K1 and antibacterial activity against Mycobacterium tuberculosis with respective IC50 values of 2.5 and 2.4 μM and displays cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells[1].
Target Antigen
Endogenous Metabolite; Parasite
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/miaosporone-a.html
Solubility
10 mM in DMSO
Smiles
O[C@]12CCC(C(C3=C(C4=O)C=CC=C3O)=O)=C4[C@@]1([H])[C@H](O)C=C(C)C2
Molecular Weight
326.34
References & Citations
[1]Saepua S, et al. Antimicrobial and Cytotoxic Angucyclic Quinones from Actinomadura miaoliensis. J Nat Prod. 2021 Nov 8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145379/Miaosporone-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145379/
Clinical Information
No Development Reported
Curated Selection
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