Miaosporone A
Miaosporone A, an angucyclic quinone, exhibits antimalarial activity against Plasmodium falciparum K1 and antibacterial activity against Mycobacterium tuberculosis with respective IC50 values of 2.5 and 2.4 μM and displays cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells[1].
Product Specifications
UNSPSC
12352005
Target
Endogenous Metabolite; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/miaosporone-a.html
Solubility
10 mM in DMSO
Smiles
O[C@]12CCC(C(C3=C(C4=O)C=CC=C3O)=O)=C4[C@@]1([H])[C@H](O)C=C(C)C2
Molecular Formula
C19H18O5
Molecular Weight
326.34
References & Citations
[1]Saepua S, et al. Antimicrobial and Cytotoxic Angucyclic Quinones from Actinomadura miaoliensis. J Nat Prod. 2021 Nov 8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Microbial Metabolite; Plasmodium
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