EIF4A3-IN-6
EIF4A3-IN-6 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII. eIF4A3-IN-6 has the potential for the research of eIF4A dependent diseases, including the research of cancer (extracted from patent US20170145026A1) [1].
Product Specifications
CAS Number
[2100133-77-3]
UNSPSC
12352005
Target
Eukaryotic Initiation Factor (eIF)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eif4a3-in-6.html
Solubility
10 mM in DMSO
Smiles
O[C@]12[C@](OC3=CC(OC)=NC(OC)=C32)(C4=CC=C(C=C4)C#N)[C@@](C5=CC=CC=C5)([H])[C@H]([C@H]1O)CN
Molecular Formula
C26H25N3O5
Molecular Weight
459.49
References & Citations
[1]Justin T. Ernst, et al. Eif4a-inhibiting compounds and methods related thereto. Patent US20170145026A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145360/eIF4A3-IN-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145360/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EIF4
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