EIF4A3-IN-6
EIF4A3-IN-6 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII. eIF4A3-IN-6 has the potential for the research of eIF4A dependent diseases, including the research of cancer (extracted from patent US20170145026A1) [1].
Product Specifications
CAS Number
[2100133-77-3]
UNSPSC
12352005
Target
Eukaryotic Initiation Factor (eIF)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eif4a3-in-6.html
Solubility
10 mM in DMSO
Smiles
O[C@]12[C@](OC3=CC(OC)=NC(OC)=C32)(C4=CC=C(C=C4)C#N)[C@@](C5=CC=CC=C5)([H])[C@H]([C@H]1O)CN
Molecular Formula
C26H25N3O5
Molecular Weight
459.49
References & Citations
[1]Justin T. Ernst, et al. Eif4a-inhibiting compounds and methods related thereto. Patent US20170145026A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EIF4
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
WFDC3 (WAP Four-disulfide Core Domain Protein 3, Putative Protease Inhibitor WAP14, dJ447F3.3) (AP)
WFDC3 (WAP Four-disulfide Core Domain Protein 3, Putative Protease Inhibitor WAP14, dJ447F3.3) (AP)
