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IDO1-IN-12

IDO1-IN-12 is a potent and orally available IDO1 inhibitor.

Product Specifications

CAS Number

2379570-48-4

UNSPSC

12352005

Target

Indoleamine 2,3-Dioxygenase (IDO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ido1-in-12.html

Solubility

10 mM in DMSO

Smiles

FC(C=C1)=CC=C1NC([C@H](C23CC(C2)(C3)NC(C4=CC(F)=C(C=C4)F)=O)C)=O

Molecular Formula

C21H19F3N2O2

Molecular Weight

388.38

References & Citations

[1]Pu Q, et al. Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors. ACS Med Chem Lett. 2020 Jul 15;11 (8) :1548-1554.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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