IDO1-IN-12
IDO1-IN-12 is a potent and orally available IDO1 inhibitor.
Product Specifications
CAS Number
2379570-48-4
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ido1-in-12.html
Solubility
10 mM in DMSO
Smiles
FC(C=C1)=CC=C1NC([C@H](C23CC(C2)(C3)NC(C4=CC(F)=C(C=C4)F)=O)C)=O
Molecular Formula
C21H19F3N2O2
Molecular Weight
388.38
References & Citations
[1]Pu Q, et al. Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors. ACS Med Chem Lett. 2020 Jul 15;11 (8) :1548-1554.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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