HDAC-IN-26
HDAC-IN-26 is a highly selective class I HDAC inhibitor with an EC50 value of 4.7 nM.
Product Specifications
CAS Number
2410542-97-9
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hdac-in-26.html
Solubility
10 mM in DMSO
Smiles
FC1=C(C=CC=C1)C2=CN=C([C@H](CCCCCC(C3=NOC=C3)=O)NC(C4CN(C4)C)=O)N2
Molecular Formula
C24H28FN5O3
Molecular Weight
453.51
References & Citations
[1]Liu J, Kelly J, Yu W, Clausen D, Yu Y, Kim H, Duffy JL, Chung CC, Myers RW, Carroll S, Klein DJ, Fells J, Holloway MK, Wu J, Wu G, Howell BJ, Barnard RJO, Kozlowski JA. Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance. ACS Med Chem Lett. 2020 Jun 22;11 (7) :1476-1483.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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