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HDAC-IN-26

HDAC-IN-26 is a highly selective class I HDAC inhibitor with an EC50 value of 4.7 nM.

Product Specifications

CAS Number

2410542-97-9

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hdac-in-26.html

Solubility

10 mM in DMSO

Smiles

FC1=C(C=CC=C1)C2=CN=C([C@H](CCCCCC(C3=NOC=C3)=O)NC(C4CN(C4)C)=O)N2

Molecular Formula

C24H28FN5O3

Molecular Weight

453.51

References & Citations

[1]Liu J, Kelly J, Yu W, Clausen D, Yu Y, Kim H, Duffy JL, Chung CC, Myers RW, Carroll S, Klein DJ, Fells J, Holloway MK, Wu J, Wu G, Howell BJ, Barnard RJO, Kozlowski JA. Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance. ACS Med Chem Lett. 2020 Jun 22;11 (7) :1476-1483.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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