IDO1-IN-11
Product Specifications
UNSPSC Description
IDO1-IN-11 is an IDO1 inhibitor with an IC50 value of 0.6 nM.
Target Antigen
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ido1-in-11.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(Cl)=CC=C1)NC2=CN=C(C3(COC3)C(NC4=CC=C(C=C4)F)=O)C=C2
Molecular Weight
425.84
References & Citations
[1]White C, et al. Strategic Incorporation of Polarity in Heme-Displacing Inhibitors of Indoleamine-2,3-dioxygenase-1 (IDO1). ACS Med Chem Lett. 2020 Mar 10;11(4):550-557.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145332/IDO1-IN-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145332/
Clinical Information
No Development Reported
CAS Number
2306411-34-5
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