IDO1-IN-11

IDO1-IN-11 is an IDO1 inhibitor with an IC50 value of 0.6 nM.

Product Specifications

CAS Number

[2306411-34-5]

UNSPSC

12352005

Target

Indoleamine 2,3-Dioxygenase (IDO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ido1-in-11.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC(Cl)=CC=C1)NC2=CN=C(C3(COC3)C(NC4=CC=C(C=C4)F)=O)C=C2

Molecular Formula

C22H17ClFN3O3

Molecular Weight

425.84

References & Citations

[1]White C, et al. Strategic Incorporation of Polarity in Heme-Displacing Inhibitors of Indoleamine-2,3-dioxygenase-1 (IDO1) . ACS Med Chem Lett. 2020 Mar 10;11 (4) :550-557.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

SM1485P 100 µg

PI 3 Kinase p85 beta (PIK3R2) Mouse Monoclonal Antibody [Clone ID: T15]

Ask

View Details

ECP7931-1 96 Tests

Pentosidine ELISA Kit

Ask

View Details

ABC-KD15584 1 Vial

Human TMEM14C knockdown cell line

Ask

View Details

475562 100 µL

ARHGEF10L (Rho Guanine Nucleotide Exchange Factor 10-like Protein)

Ask

View Details