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Heterobivalent ligand-1

Product Specifications

UNSPSC Description

Heterobivalent ligand-1 (compound 26) is a heterobivalent ligand for the Adenosine A 2A-dopamine D 2 receptor heteromer (KDB1 A2AR=2.1 nM, KDB1 D2R= 0.13 nM)[1].

Target Antigen

Adenosine Receptor; Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/heterobivalent-ligand-1.html

Solubility

10 mM in DMSO

Smiles

O=C(CN(CC(OC)=O)CC(NCCOCCOCCOCCOCCOCCNC(COC1=CC=C(CCCN2N=CC3=C2N=C(N)N4C3=NC(C5=CC=CO5)=N4)C=C1)=O)=O)NCCOCCOCCOCCOCCOCCNC(CCC(NC6=CC=C(CCN7CN(C8=CC=CC=C8)C9(CCN(CCCC(C%10=CC=C(F)C=C%10)=O)CC9)C7=O)C=C6)=O)=O

Molecular Weight

1741.95

References & Citations

[1]Pulido D, et al. Heterobivalent Ligand for the Adenosine A2A-Dopamine D2 Receptor Heteromer. J Med Chem. 2022;65(1):616-632.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-145308/Heterobivalent-ligand-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-145308/

Clinical Information

No Development Reported

CAS Number

2888568-58-7

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