DX3-235
DX3-235 is an oxidative phosphorylation (OXPHOS) inhibitor. DX3-235 shows nanomolar inhibition of complex I function and ATP production in a galactose-containing medium resulting in significant cytotoxicity[1].
Product Specifications
CAS Number
2749555-39-1
UNSPSC
12352005
Target
Mitochondrial Metabolism; Oxidative Phosphorylation
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dx3-235.html
Solubility
10 mM in DMSO
Smiles
CC(C1=NOC(N2CCN(CC2)C([C@H]3CN(CCC3)S(=O)(C4=CC=C(C=C4)S(C(CC)CC)(=O)=O)=O)=O)=N1)C
Molecular Formula
C26H39N5O6S2
Molecular Weight
581.75
References & Citations
[1]Xue D, et al. Discovery and Lead Optimization of Benzene-1,4-disulfonamides as Oxidative Phosphorylation Inhibitors. J Med Chem. 2022;65 (1) :343-368.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rabbit Monoclonal CD40 Ligand/TNFSF5 Antibody (YMF323.6) [Alexa Fluor 750]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NBP2-81114AF750 0.1 mL
Rabbit Monoclonal CD40 Ligand/TNFSF5 Antibody (YMF323.6) [Alexa Fluor 750]
Sign In for Pricing
View Details 
MBS730698-01 48 Well
Guinea pig Chorionic Gonadotrophin beta ELISA Kit
Sign In for Pricing
View Details