Mycobactin-IN-2

Mycobactin-IN-2 (compound 49) is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-2 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway[1].

Product Specifications

CAS Number

[421573-09-3]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mycobactin-in-2.html

Solubility

10 mM in DMSO

Smiles

BrC1=CC=C(C2NN=C(C2)C3=C(O)C=CC=C3)C=C1

Molecular Formula

C15H13BrN2O

Molecular Weight

317.18

References & Citations

[1]Shyam M, et, al. Mycobactin Analogues with Excellent Pharmacokinetic Profile Demonstrate Potent Antitubercular Specific Activity and Exceptional Efflux Pump Inhibition. J Med Chem. 2022 Jan 13;65 (1) :234-256.