Mycobactin-IN-1

Mycobactin-IN-1 (compound 44), a pyrazoline analogue, is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-1 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway[1].

Product Specifications

CAS Number

[65840-95-1]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mycobactin-in-1.html

Purity

98.96

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C(C2NN=C(C2)C3=C(O)C=CC=C3)C=C1

Molecular Formula

C15H13ClN2O

Molecular Weight

272.73

References & Citations

[1]Mousumi Shyam, et al. Mycobactin Analogues with Excellent Pharmacokinetic Profile Demonstrate Potent Antitubercular Specific Activity and Exceptional Efflux Pump Inhibition.J Med Chem. 2022 Jan 13;65 (1) :234-256.