ATP-PEG8-Biotin

ATP-PEG8-Biotin is a PEG-based linker that incorporates ATP. ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation[1][2].

Product Specifications

UNSPSC

12352005

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/atp-peg8-biotin.html

Purity

96.34

Solubility

10 mM in DMSO

Smiles

O[C@H]([C@@H]1O)[C@@H](O[C@@H]1CO[P](O[P](O[P](O)(OCCOCCOCCOCCOCCOCCOCCOCCNC(CCCC[C@@H]2SCC(C2N3)NC3=O)=O)=O)(O)=O)(O)=O)N4C5=NC=NC(N)=C5N=C4

Molecular Formula

C36H63N8O22P3S

Molecular Weight

1084.91

References & Citations

[1]Swennen EL, et al. Immunoregulatory effects of adenosine 5'-triphosphate on cytokine release from stimulated whole blood. Eur J Immunol. 2005 Mar;35 (3) :852-8.|[2]M J L Bours, et al. Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther. 2006 Nov;112 (2) :358-404.