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AChE-IN-4

AChE-IN-4 shows the acetylcholine esterase inhibition (AChEI) with an IC50 value of 24.1 μM.

Product Specifications

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ache-in-4.html

Solubility

10 mM in DMSO

Smiles

[H][C@]12CSCN1[C@@]3([C@@](C(C4=C(N(N=C4)C5=CC=CC=C5)C)=O)([C@@]2(C6=CNC7=C6C=C(C=C7)Br)[H])[H])C(NC8=CC=C(C=C83)[N+]([O-])=O)=O

Molecular Formula

C32H25BrN6O4S

Molecular Weight

669.55

References & Citations

[1]Islam MS, et al. Construction of Spirooxindole Analogues Engrafted with Indole and Pyrazole Scaffolds as Acetylcholinesterase Inhibitors. ACS Omega. 2021 Nov 12.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE

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