GPBAR1-IN-3
GPBAR1-IN-3 (Compound 14) is a selective GPBAR1 agonist (EC50=0.17 μM) and a CysLT1R antagonist[1].
Product Specifications
CAS Number
[2760546-05-0]
UNSPSC
12352005
Target
G protein-coupled Bile Acid Receptor 1; Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Others
Assay Protocol
https://www.medchemexpress.com/gpbar1-in-3.html
Solubility
10 mM in DMSO
Smiles
CC(CC)COC1=CC(OCC2=NC3=C(C=C2)C=CC=C3)=CC=C1
Molecular Formula
C21H23NO2
Molecular Weight
321.41
References & Citations
[1]Fiorillo B, et al. Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1. J Med Chem. 2021 Nov 12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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