PfPKG-IN-1
PfPKG-IN-1 is a imidazole-based inhibitor of Plasmodium falciparum cGMP-dependent protein kinase (PfPKG) .
Product Specifications
CAS Number
[2866493-89-0]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pfpkg-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC=CS1)N(CC2)C[C@@H]2NC3=NC(N4C(C5=CC=CC(Cl)=C5)=NC(C6CC6)=C4)=CC=N3
Molecular Formula
C24H22ClN7OS
Molecular Weight
492.00
References & Citations
[1]Yadav Bheemanaboina RR, et al. Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase. ACS Med. Chem. Lett. 2021 Nov 15.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Plasmodium
Curated Selection
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