CP-628006
Product Specifications
UNSPSC Description
CP-628006, a small molecule CFTR potentiator, restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR.
Target Antigen
CFTR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cp-628006.html
Solubility
10 mM in DMSO
Smiles
CC(N=CC=C1)=C1CNC(C2=CC=C(C(CC[C@]3([H])C[C@](O)(CC4)CCC(F)(F)F)=C2)[C@@]34CC5=CC=CC=C5)=O
Molecular Weight
536.63
References & Citations
[1]Liu J, et al. A small molecule CFTR potentiator restores ATP-dependent channel gating to the cystic fibrosis mutant G551D-CFTR. Br J Pharmacol. 2021 Oct 13.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145126/CP-628006-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145126/
Clinical Information
No Development Reported
CAS Number
305822-08-6
Curated Selection
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