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PROTAC ER Degrader-10

PROTAC ER Degrader-10 is a potent PROTAC ER degrader and can be used for cancer research. PROTAC ER Degrader-10 is extracted from patent WO2021133886, example 36.

Product Specifications

CAS Number

2504911-58-2

UNSPSC

12352005

Target

Estrogen Receptor/ERR; PROTACs

Type

Reference compound

Related Pathways

PROTAC; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-er-degrader-10.html

Solubility

10 mM in DMSO

Smiles

OC1=CC=C([C@@](C2=CC=C(N3CCC(CC3)CN4CCN(C5=CC=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=C5)CC4)C=C2)([H])[C@@](C8=CC=CC=C8)([H])CO9)C9=C1

Molecular Formula

C44H45N5O6

Molecular Weight

739.86

References & Citations

[1]Jie Fan, et al. Combinations of estrogen receptor degraders and cyclin-dependent kinase inhibitors for treating cancer. Patent WO2021133886.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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