HBV-IN-9
HBV-IN-9 is a potent HBsAg (HBV Surface antigen) inhibitor (IC50=10 nM) and HBV DNA production inhibitor (IC50=0.15 nM in HepG2.2.15 cells) [1]. From patent WO2018001952A1, example 20.
Product Specifications
CAS Number
2170998-69-1
UNSPSC
12352005
Target
HBV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hbv-in-9.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(N2CCC(C2)OC)=CC(N3CCC4=C(C3C)C=NC(C5=NC=CC=N5)=N4)=N1
Molecular Formula
C22H24FN7O
Molecular Weight
421.47
References & Citations
[1]Zhanling CHENG, et al. Novel tetrahydropyridopyrimidines for the treatment and prophylaxis of hbv infection. WO2018001952A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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