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HBV-IN-9

HBV-IN-9 is a potent HBsAg (HBV Surface antigen) inhibitor (IC50=10 nM) and HBV DNA production inhibitor (IC50=0.15 nM in HepG2.2.15 cells) [1]. From patent WO2018001952A1, example 20.

Product Specifications

CAS Number

2170998-69-1

UNSPSC

12352005

Target

HBV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hbv-in-9.html

Solubility

10 mM in DMSO

Smiles

FC1=CC(N2CCC(C2)OC)=CC(N3CCC4=C(C3C)C=NC(C5=NC=CC=N5)=N4)=N1

Molecular Formula

C22H24FN7O

Molecular Weight

421.47

References & Citations

[1]Zhanling CHENG, et al. Novel tetrahydropyridopyrimidines for the treatment and prophylaxis of hbv infection. WO2018001952A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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