SOS1-IN-4
SOS1-IN-4 is a potent SOS1 inhibitor with an IC50 of 56 nM for KRAS-C12C/SOS1 interaction (WO2021228028 A1, example 65) [1].
Product Specifications
CAS Number
2738392-83-9
UNSPSC
12352005
Target
Ras; SOS1
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sos1-in-4.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=NC(C)=NC(N[C@H](C)C3=CC(N)=CC(C(F)F)=C3)=C2C=C1P4(CCCCC4)=O
Molecular Formula
C24H29F2N4O2P
Molecular Weight
474.48
References & Citations
[1]Sos1 inhibitor containing phosphorus. WO2021228028A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
Frequently Asked Questions
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