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SOS1-IN-3

SOS1-IN-3 is a potent SOS1 (son of sevenless homolog 1) inhibitor with an IC50 of 5 nM. SOS1-IN-3 has anticancer effects (WO2019122129A1; compound I-1) [1].

Product Specifications

CAS Number

2359689-76-0

UNSPSC

12352005

Target

Ras; SOS1

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sos1-in-3.html

Solubility

10 mM in DMSO

Smiles

C[C@H](C1=C(C(C(F)F)=CC=C1)F)NC(C2=CN3C4(CC4)C)=NC(C)=NC2=CC3=O

Molecular Formula

C21H21F3N4O

Molecular Weight

402.41

References & Citations

[1]Juergen Ramharter, et al. Novel benzylamino substituted pyridopyrimidinones and derivatives as sos1 inhibitors. WO2019122129A1

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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