SOS1-IN-3
SOS1-IN-3 is a potent SOS1 (son of sevenless homolog 1) inhibitor with an IC50 of 5 nM. SOS1-IN-3 has anticancer effects (WO2019122129A1; compound I-1) [1].
Product Specifications
CAS Number
[2359689-76-0]
UNSPSC
12352005
Target
Ras; SOS1
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sos1-in-3.html
Solubility
10 mM in DMSO
Smiles
C[C@H](C1=C(C(C(F)F)=CC=C1)F)NC(C2=CN3C4(CC4)C)=NC(C)=NC2=CC3=O
Molecular Formula
C21H21F3N4O
Molecular Weight
402.41
References & Citations
[1]Juergen Ramharter, et al. Novel benzylamino substituted pyridopyrimidinones and derivatives as sos1 inhibitors. WO2019122129A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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