HPK1-IN-9
HPK1-IN-9 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-9 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 112) [1].
Product Specifications
CAS Number
[2734168-78-4]
UNSPSC
12352005
Target
MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hpk1-in-9.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CC(C1)N(C)C)C2=CC=C(C3=CNC4=C3N=C(C5=CC=C6C(OCC7N6CCN(C7)C)=C5)C=N4)C=C2
Molecular Formula
C30H33N7O2
Molecular Weight
523.63
References & Citations
[1]Xie, Yuli, et al. Hpk1 inhibitor and preparation method and use thereof. Patent WO2021213317A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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