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RET-IN-6

RET-IN-6 is a potent RET (rearranged during transfection) inhibitor with an IC50 of 4.57 nM (CN113461670A, compound 321) [1].

Product Specifications

CAS Number

2715208-83-4

UNSPSC

12352005

Target

RET

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ret-in-6.html

Solubility

10 mM in DMSO

Smiles

CN1C=C(C=N1)C2=CC3=C(C=CC=N3)C(C4=CN=C(N(CC5CC6)CC6N5CC7=CC=CC=C7)C=C4)=N2

Molecular Formula

C30H29N7

Molecular Weight

487.60

References & Citations

[1]Novel compounds as inhibitors of rearrangement kinase during transfection. CN113461670A.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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