KRAS G12C inhibitor 23
KRAS G12C inhibitor 23 is a KRAS G12C inhibitor. KRAS G12C inhibitor 23 inhibits H358 cells with an IC50 of 491 nM (WO2021218939A1, compound 1) [1].
Product Specifications
CAS Number
[2735721-00-1]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-23.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=C(N=CC=C2C)C(C)C)C3=C(OCC4=CC=CC=C45)C5=C(F)C=C3C(N6[C@H](CN(CC6)C(C=C)=O)C)=N1
Molecular Formula
C32H32FN5O3
Molecular Weight
553.63
References & Citations
[1]Fused ring compound and application thereof in medicine. WO2021218939A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
More Discoveries
Explore Other Products
Browse additional items from our catalog
39027126 3x 1.0µg DNA
RGD1308134 CRISPRa sgRNA lentivector (set of three targets)(Rat)
Sign In for Pricing
View Details 
RC224616L3 10 µg
Ninein (NIN) (NM_016350) Human Tagged Lenti ORF Clone
Sign In for Pricing
View Details 
